Ortho-substituted benzoylguanidines, process for their preparati

Details Ortho-substituted benzoylguanidines, process for their preparati Ortho-substituted benzoylguanidines, process for their preparati

1997-06-03

2000-01-04

O'Sullivan, Peter

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514307, 514309, 514311, 514312, 514350, 514351, 514522, 546141, 546145, 546157, 546170, 546175, 546290, 546298, 546300, 558415, 560100, 560106, 560251, A61K 31275, A61K 3122, A61K 3124

Patent

active

060110635

ABSTRACT:
Ortho-substituted benzoylguanidines of the formula I ##STR1## in which R(1) to R(5) have the meanings given in the claims, are suitable as antiarrhythmic pharmaceuticals having a cardioprotective component for infarct prophylaxis and for infarct treatment and also for the treatment of angina pectoris. They also inhibit in a preventive manner the pathophysiological processes in the formation of ischemically induced damage, in particular in the illicitation of ischemically induced cardiac arrhythmias.

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