Organometallic ligands for the localization and quantification o

Details Organometallic ligands for the localization and quantification o Organometallic ligands for the localization and quantification o

1997-05-07

2000-04-25

MacMillan, Keith D.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

424 91, 534 10, 534 12, 534 14, 534883, 556 45, A61K 5100, A61K 4900, C07F 1300

Patent

active

060541148

ABSTRACT:
Novel organometallic compounds for binding amyloid are described. Methods using such compounds for determining by imaging the localization or quantification of amyloid fibrils in a mammal, for diagnosing the degree of progression of Alzheimer's disease in a mammal, for monitoring the response to a therapy in a mammal having Alzheimer's disease, for identifying an agent useful for treating Alzheimer's disease, for treating Alzheimer's disease, and for detecting the presence of the infectious form of the prion protein, are also described.

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