Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills
Patent
1991-12-18
1993-04-06
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Tablets, lozenges, or pills
424468, 424472, A61K 924
Patent
active
052001946
ABSTRACT:
An osmotic device (10) for delivering a beneficial drug, such as an anti-microbial drug, into the mouth of a human patient is disclosed. The device (10) has a size and shape adapting it to be comfortably retained in the mouth for extended periods of time. The device comprises a thin semipermeable membrane wall (12) surrounding a compartment (13) housing a beneficial agent (14) that has at least some degree of solubility in aqueous biological fluids, e.g., saliva, and a fibrous support material (15) composed of hydrophilic water-insoluble fibers. A passageway (17) in the wall (12) connects the agent 14) with the exterior of the device (10). The wall (12) is permeable to the passage of aqueous biological fluid but substantially impermeable to the passage of the fibrous support material (15). The fibrous support material (15), once hydrated, provides a rigid support for the thin semipermeable wall (12) and prevents the device (10) from prematurely releasing the beneficial agent (14) even when the device (10) is subjected to patient sucking.
REFERENCES:
patent: 2799241 (1957-07-01), Wurster
patent: 3133132 (1964-05-01), Loeb et al.
patent: 3173876 (1965-03-01), Zobrist
patent: 3276586 (1966-10-01), Rosaen
patent: 3541005 (1970-11-01), Strathmann et al.
patent: 3541006 (1970-11-01), Bixler et al.
patent: 3546142 (1970-12-01), Michaels et al.
patent: 3845770 (1974-11-01), Theeuwes et al.
patent: 3916899 (1975-11-01), Theeuwes et al.
patent: 4111202 (1978-09-01), Theeuwes
patent: 4160020 (1979-07-01), Ayer et al.
patent: 4327725 (1982-05-01), Cortese et al.
patent: 4568535 (1986-02-01), Loesche
patent: 5021053 (1991-06-01), Barclay et al.
Bhatti Gurdish K.
Edgren David E.
ALZA Corporation
Duvall Jean M.
Horne Leon R.
Miller D. Byron
Page Thurman K.
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