Surgery – Diagnostic testing – Measuring or detecting nonradioactive constituent of body...
Reexamination Certificate
2007-04-17
2007-04-17
Winakur, Eric F. (Department: 3768)
Surgery
Diagnostic testing
Measuring or detecting nonradioactive constituent of body...
C600S310000
Reexamination Certificate
active
10170921
ABSTRACT:
An optical sampling interface system minimizes and compensates error resulting from sampling variations and measurement site state fluctuations. Components include: An optical probe placement guide having an aperture wherein the optical probe is received, facilitates repeatable placement accuracy on surface of a tissue measurement site with minimal, repeatable disturbance to surface tissue. The aperture creates a tissue meniscus that minimizes interference due to surface irregularities and controls variation in tissue volume sampled; an occlusive element placed over the tissue meniscus isolates the meniscus from environmental fluctuations, stabilizing hydration at the site and thus, surface tension; an optical coupling medium eliminates air gaps between skin surface and optical probe; a bias correction element applies a bias correction to spectral measurements, and associated analyte measurements. When the guide is replaced, a new bias correction is determined for measurements done with the new placement. Separate components of system can be individually deployed.
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Acosta George
Blank Thomas B.
Lorenz Alexander D.
Makarewicz Marcy
Mattu Mutua
Glenn Michael A.
Glenn Patent Group
Sensys Medical Inc.
Winakur Eric F.
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