Optical fluorescent imaging

Details Optical fluorescent imaging Optical fluorescent imaging

2006-05-19

2009-10-06

Jones, D L (Department: 1618)

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Diagnostic or test agent produces in vivo fluorescence

C424S001110, C424S001650, C424S009100

Reexamination Certificate

active

07597878

ABSTRACT:
Compounds and methods are disclosed that are useful for noninvasive imaging in the near-infrared (NIR) spectral range. The NIR is highly sensitive for tumor detection and tracking. The application discloses targeting a tumor-enriched cell surface receptor with a ligand-conjugated fluorescent probe, which specifically allows detection of the tumor relative to the negligible animal autofluorescence.

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