Optical blood culture sensor

Details Optical blood culture sensor Optical blood culture sensor

1994-08-15

2000-06-13

Beisner, William H.

Chemistry: molecular biology and microbiology

Apparatus

Including measuring or testing

4352887, 435 34, C12M 134

Patent

active

060748702

ABSTRACT:
A culture medium and blood specimen are introduced into a sealable glass vial having a head space gas mixture such that a change in the gas mixture composition can be monitored by a chemically sensitive material in the vial comprising a mixture of two fluorescent sensor materials. The first sensor material exhibits a long fluorescence decay time and/or a fluorescence intensity that depend on a first chemical parameter, such as oxygen concentration. The second sensor material exhibits a fluorescence intensity that depends on a second chemical parameter, such as pH or carbon dioxide concentration, the fluorescence decay time of the second sensor material being extremely short.

REFERENCES:
patent: 4791310 (1988-12-01), Honig et al.
patent: 4945060 (1990-07-01), Turner et al.
patent: 5372784 (1994-12-01), Morris et al.
patent: 5372936 (1994-12-01), Fraatz et al.

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