Opioid peptides derived from wheat proteins

Details Opioid peptides derived from wheat proteins Opioid peptides derived from wheat proteins

1993-05-14

1994-08-16

Lilling, Herbert J.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Enzymatic production of a protein or polypeptide

514 17, 514 18, 530329, 530330, A61K 3700, C12P 2106

Patent

active

053386680

ABSTRACT:
Disclosed are opioid peptides recovered from hydrolysates of wheat proteins with an acid protease and further a neutral or alkaline protease. Of those peptides, the structure of four opioid peptides was identified by the amino acid sequence of Gly-Tyr-Tyr-Pro (SEQ ID NO: 1), Gly-Tyr-Tyr-Pro-Thr (SEQ ID NO: 2), Gly-Tyr-Tyr-Pro-Thr-Ser (SEQ ID NO: 3) or Tyr-Pro-Ile-Ser-Leu (SEQ ID NO: 4). They are useful as a medicine such as narcotic, analgesic or the like.

REFERENCES:
Biotech Abs. 86-00510 Ajinomoto J60164496 (Aug. 1985).

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