Oligopeptide derivatives of ipoxantine endowed with immunomodula

Details Oligopeptide derivatives of ipoxantine endowed with immunomodula Oligopeptide derivatives of ipoxantine endowed with immunomodula

1991-06-28

1994-03-29

Lee, Lester L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen bonded directly to ring carbon of the purine ring...

544276, 544275, 530330, 530331, C07K 506

Patent

active

052986217

ABSTRACT:
Ipoxantine derivatives of general formula (I): ##STR1## both as racemate and chiral forms and the salts thereof with pharmacologically acceptable cations, wherein n is an integer comprised between 2 and 6, and A is the residue of a dipeptide, tripeptide, tetrapeptide and pentapeptide selected, respectively, from the groups consisting of:

REFERENCES:
patent: 4567182 (1986-01-01), Ferraris
Il Farmaco, vol. 45, No. 1, 1990, pp. 39-47, R. Stradi, et al., "Synthetic Biological Response Modifiers; Part 1. Synthesis and Immunomodulatory Properties of Some N2-(w(Hypoxanthin-9-YL)Alkoxycarbonyl-L-Arginines".

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