Octacyclodepsipeptides having an endoparasiticidal action

Details Octacyclodepsipeptides having an endoparasiticidal action Octacyclodepsipeptides having an endoparasiticidal action

1995-05-31

1998-02-10

Tsang, Cecilia J.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Peptides with at least one nonpeptide bond other than a...

530330, 530328, 514 16, 514 18, A61K 3815, C07K 1100

Patent

active

057170630

ABSTRACT:
The present invention relates to compounds of the general formula (I) ##STR1## in which R.sup.1 and R.sup.12 represent the same or different radicals selected from the group of C.sub.2-9 -alkyl, C.sub.1-8 -halogeno-alkyl, C.sub.3-6 -cycloalkyl, aralkyl or aryl,

REFERENCES:
patent: 5525591 (1996-06-01), Scherkenbeck et al.
Isogi et al. "Bassianolide: Synthesis of its Analogs and NMR Studies", Peptide Chemistry, pp. 165-170, 1979.
Ivanov et al. Peptides, Proc. European Symp. vol. 6, pp. 337-350, 1963.
Losse, G. & G. Bachmann: Synthesis of depsipeptides. Chem. Ber. 97: 2671-2680, 1964.
Ierchen et al., "Stereoselective Synthese von D-alpha-Hydroxycarbonsauren BZW. D-alapha-Hydroxycarbonsauren Ethaltenden Depsipeptiden aus L-Aminosauren", Tetrahedron Letters, vol. 26, No. 43, pp. 5257-5260, 1985.
Journal Antibiot. 1992, 692-697.
Synthesis of Amino Acids, Peptides, and Proteins, vol. 69, 1968, pp. 9114-9115.
Tetrahedron Letters, vol. 26, No. 43, pp. 5257-5260, 1985.

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