O-carbamoyl-phenylalaninol having substituent at benzene ring, i

Details O-carbamoyl-phenylalaninol having substituent at benzene ring, i O-carbamoyl-phenylalaninol having substituent at benzene ring, i

1996-04-09

2000-10-31

Shippen, Michael L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560163, C07C26100

Patent

active

061405329

ABSTRACT:
O-Carbamoyl-phenylalaninol having substituent at benzene ring, represented by the general formula I, and pharmaceutically useful salts thereof, which are useful for the prophylaxis and treatment of CNS disorder including depression and anxiety, are disclosed: ##STR1## wherein R is lower alkyl containing 1 to 8 carbon atoms, halogen such as F, Cl and I, alkoxy containing 1 to 3 carbon atoms, thioalkoxy containing 1 to 3 carbon atoms, nitro, hydroxy, or trifluorocarbon, and x is an integer of 1 to 3, with a proviso that R is the same or different when x is 2 or 3.

REFERENCES:
patent: 5705640 (1998-01-01), Choi
patent: 5756817 (1998-05-01), Choi

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