Nucleophilic substitution process for fluoronitroaralkyloxazolin

Details Nucleophilic substitution process for fluoronitroaralkyloxazolin Nucleophilic substitution process for fluoronitroaralkyloxazolin

1984-11-13

1988-01-26

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548238, 548239, C07D26308

Patent

active

047217901

ABSTRACT:
Fluoronitroaralkyloxazolines are prepared by reacting a fluoronitroaromatic compound with an alpha-substituted 2-alkyloxazoline in an inert solvent and in the presence of a base. Fluoronitroaralkyloxazolines are useful intermediates for the synthesis of pharmaceuticals, such as flurbiprofen.

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