Nucleic acids of the human ABCC11 gene, vectors containing...

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Reexamination Certificate

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C435S320100, C435S471000, C435S252300, C435S325000, C435S071100, C530S333000, C530S351000

Reexamination Certificate

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06893841

ABSTRACT:
The present invention relates to nucleic acids corresponding to various exons of the ABCC11 gene as well as the cDNA encoding the novel full length of ABCC11 protein. The invention also relates to means for the detection of polymorphisms in general, and of mutations in particular, in the ABCC11 gene or in the corresponding protein produced by the allelic form of the ABCC11 gene.

REFERENCES:
Schuetz et al. MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs. Nature Medicinie, vol. 5, No. 9, pp. 1048-1051, Sep. 1999.
Wijnhods et al. Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs. PNAS, vol. 97, No. 13, pp. 7476-7481, Jun. 2000.

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