Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1995-06-05
2000-12-26
Kunz, Gary L.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 697, 4353201, 435325, 4352523, 43525411, 536 231, 536 234, 536 235, 530300, 530 35, C12N 1512, C12N 1510, C12N 500, C07K 14475
Patent
active
061657476
ABSTRACT:
The present invention concerns the discovery that proteins encoded by a family of vertebrate genes, termed here hedgehog-related genes, comprise morphogenic signals produced by tissue patterning centers, and are involved in the formation of ordered spatial arrangements of differentiated tissues in vertebrates. The present invention makes available compositions and methods that can be utilized, for example to generate and/or maintain an array of different vertebrate tissue both in vitro and in vivo.
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Bumcrot David A.
Ingham Philip W.
Marti-Gorostiza Elisa
McMahon Andrew P.
Tabin Clifford J.
Imperial Cancer Research Technology Ltd.
Kaufman Claire M.
Kunz Gary L.
President & Fellows of Harvard College
Varma Anita
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