Novel uracil derivatives, process for preparing the same and a p

Details Novel uracil derivatives, process for preparing the same and a p Novel uracil derivatives, process for preparing the same and a p

1981-08-10

1983-11-15

Moyer, Donald B.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544311, 544312, 544313, 544314, 542468, A61K 31505, C07D23910

Patent

active

044155735

ABSTRACT:
Novel uracil derivatives of the formula ##STR1## (wherein R.sub.1, R.sub.2 R.sub.3 and X are defined in the description) and their pharmaceutically acceptable salts, process for preparing the same and pharmaceutical composition containing the same are disclosed. The uracil derivatives have good antitumor activity and, therefore, are useful as antitumor preparation.

REFERENCES:
patent: 4122251 (1978-10-01), Misaki et al.
Chemical Abstracts, vol. 94, No. 21, Jun. 2, 1981, p. 723, Abstract No. 175027g, Karpeiskii, M. Ya. et al.
J. Med. Chem., vol. 24, No. 6, Jun. 8, 1981, pp. 753-756, Kelley, J. L. et al.
J. Biol. Chem., vol. 253, No. 24, 1978, pp. 8721-8727, Fyfe, J. A. et al.

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