Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1994-06-29
1997-08-12
Walsh, Stephen
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 697, 4351723, 4352542, 514 2, 536 2351, 530399, C12N 1509, C12N 1581
Patent
active
056564589
ABSTRACT:
Methods and compositions are provided for producing, in yeast, basic and acidic fibroblast growth factors (FGF's) that are at least partially acetylated at their amino-termini. DNA constructs containing genes coding for the FGF polypeptides under transcriptional control of a regulatable promoter are expressed in transformed host yeast cells to achieve high yields of the processed FGF's.
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Blackburn Robert P.
Chiron Corporation
Robins Roberta L.
Savereide Paul B.
Teng Sally P.
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