Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1976-11-10
1978-02-07
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
A61K 31135
Patent
active
040727599
ABSTRACT:
A compound having the formula: ##STR1## wherein Ring A is monohydroxyphenyl, or a pharmaceutically acceptable acid addition salt thereof is prepared by catalytic hydrogenation of a compound having the formula: ##STR2## wherein A' is monobenzyloxyphenyl, and Y is carbonyl or hydroxymethylene. The compound (I) in which Ring A is 4-hydroxyphenyl or 3-hydroxyphenyl is useful as a cardiotonic agent. On the other hand, the compound (I) in which Ring A is 2-hydroxyphenyl is useful as an anti-diabetic agent.
REFERENCES:
patent: 3255249 (1966-06-01), Howe et al.
patent: 3869474 (1975-03-01), Miura et al.
Hoshiyama Masao
Ikezaki Muneyoshi
Ito Nobuo
Nagao Taku
Nakajima Hiromichi
Friedman Stanley J.
Tanabe Seiyaku Co. Ltd.
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