Novel anti-diarrheal 4-azatricyclo[4.3.1.1.sup.3,8 ] undecane de

Details Novel anti-diarrheal 4-azatricyclo[4.3.1.1.sup.3,8 ] undecane de Novel anti-diarrheal 4-azatricyclo[4.3.1.1.sup.3,8 ] undecane de

1977-08-02

1978-04-25

Randolph, John D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260296D, C07D22300, C07D40302

Patent

active

040862275

ABSTRACT:
The present invention, comprehends a method for treating diarrhea comprising administering to an animal in need of anti-diarrheal treatment an effective anti-diarrheal amount of a compound of the formula ##STR1## and acid addition salts thereof wherein Y is alkylene containing 1-4 carbon atoms; R.sub.2 and R.sub.3 together with N is a heterocyclic ring system comprising azamonocyclic ring of the formula ##STR2## wherein Z is phenylhydroxymethylmethylene, phenylhydroxymethylene, phenylcarboxymethylene, phenylcarbalkoxymethylene or azabicycloalkyl or phenyl or hydroxyl substituted azabicycloalkyl containing 6-9 carbon atoms and containing at least 5 atoms in each ring of the azabicycloalkyl or 4-azatricyclo[4.3.1.1.sup.3,8 ]undec-4-yl; Ar.sub.1 and Ar.sub.2 are phenyl, halo-substituted phenyl, (lower alkyl) substituted phenyl, pyridyl, thienyl or furyl, and Ar.sub.3 is phenyl, halo-substituted phenyl, (lower alkyl) substituted phenyl, pyridyl, thienyl, furyl, pyrrolyl, imidazoyl, oxazolinyl, oxazolinyl, thiazolinyl, thiazolyl, 1,2,4-oxodiazolyl, and isoxazolinyl. The present invention also comprehends novel compounds included in the above formula.

REFERENCES:
patent: 3917615 (1975-11-01), Adelstein
patent: 3998832 (1976-12-01), Adelstein et al.

Affiliated with

Also associated with

Rating

Novel anti-diarrheal 4-azatricyclo[4.3.1.1.sup.3,8 ] undecane de does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Novel anti-diarrheal 4-azatricyclo[4.3.1.1.sup.3,8 ] undecane de, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel anti-diarrheal 4-azatricyclo[4.3.1.1.sup.3,8 ] undecane de will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2419917