Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2001-02-28
2008-08-26
Qian, Celine X (Department: 1636)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C435S320100, C435S325000
Reexamination Certificate
active
07417137
ABSTRACT:
The invention relates to the field of cancer therapy and diagnosis, in particular of carcinomas. The invention provides an isolated and/or recombinant nucleic acid comprising a tissue specific promoter or functional fragment thereof allowing for expression of a nucleic acid of interest operably linked to said promoter or functional fragment thereof in a cancer cell wherein said expression in said cancer cell is essentially carcinoma selective.
REFERENCES:
patent: WO 98/00013 (1998-01-01), None
patent: WO 98/01350 (1998-04-01), None
Chen et al. J. Clin. Invest., 1996. vol. 98, No. 11, pp. 2539-2548.
Verma et al. (1997, Nature, vol. 389, pp. 239-242).
Anderson et al.(1998, Nature, vol. 392, pp. 25-30).
Palu et al.(1999, Journal of Biotechnology, vol. 68, pp. 1-13).
Siemieniako et al (1992), BBRC, vol. 186, No. 3, pp. 1353-1361).
M. Balzar et al, “The Biology of the 17-1A Antigen (Ep-CAM)”, Journal of Molecular Medicine, vol. 77, No. 10, Oct. 1999, pp. 699-712.
B. Birren et al, “Homo sapiensChromosome 4, clone RP11-77N9 mag 4, Working Draft Sequence, 13 unordered pieces”, EMBL Database Entry AC018614; Accession No. AC018614, Dec. 16, 1999.
M. Fornaro et al, “Cloning of the Gene Encoding Trop-2, a Cell-Surface Glycoprotein Expressed by Human Carcinomas”, International Journal of Cancer, vol. 62, No. 5, Sep. 4, 1995, pp. 610-618.
A.J. Linnenbach et al, “Retroposition in a Family of Carcinoma-Associated Antigen Genes”, Molecular and Cellular Biology, vol. 13, Mar. 1993, pp. 1507-1515.
B. Siemieniako et al, “Nuclear Proteins from Capan-2 Cell Line Form Specific Complexes with the 17-1A Antigen Gene Promoter”, Biochemical and Biophysical Research Communications, vol. 186, No. 3, Aug. 14, 1992, pp. 1353-1361.
R.H. Waterston, “Homo sapiensChromosome 2 Clone RP11-295PS, Working Draft Sequence, 8 Unordered Pieces” EMBL database Online! Accession No. AC079775.
de Leij Lou Franciscus M. H.
Dokter Willem Hendrik A.
Harmsen Martin Conrad
McLaughlin Pamela Marijke J.
Ruiters Marcel Herman J.
Banner & Witcoff , Ltd.
Qian Celine X
Synvolux IP B.V.
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