Non invasive method of electroporation mediated by carbon...

Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Cell membrane or cell surface is target

Reexamination Certificate

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C435S306100

Reexamination Certificate

active

08058043

ABSTRACT:
A non-invasive method for the electroporation of cells contained in a substrate wherein the cells are placed in contact with carbon nanotubes and then said substrate is subjected to the action of two orthogonal pulsed electric fields generated by means of two pairs of electrodes in contact with said substrate according to a specific time sequence in such a way that, when a pair of electrodes is active, the other pair of electrodes is deactivated and vice versa. A device for performing electroporation according to this method.

REFERENCES:
patent: 102004063150 (2006-07-01), None
patent: 2006/086672 (2006-08-01), None
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Yantzi, J.D., et al., Carbon nanotube enhanced pulsed electric field electroporation for biomedical applications, Proceedings of the IEEE International Conference on Mechatronics & Automation, Niagara Falls, Canada, Jul. 2005, 1872-1877.
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PCT Search Report for PCT/IB2007/054754 in the name of Scuola Superiore di Studi Universitari e Di Perfezionamento Sant'Anna filed on Nov. 22, 2007.
PCT Written Opinion for PCT/IB2007/054754 in the name of Scuola Superiore di Studi Universitari e Di Perfezionamento Sant'Anna filed on Nov. 22, 2007.

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