Non-invasive blood glucose sensors using a magneto-resonance...

Details Non-invasive blood glucose sensors using a magneto-resonance... Non-invasive blood glucose sensors using a magneto-resonance...

2005-07-11

2009-12-22

Marmor, II, Charles A (Department: 3735)

Surgery

Diagnostic testing

Measuring or detecting nonradioactive constituent of body...

C600S347000, C324S307000

Reexamination Certificate

active

07635331

ABSTRACT:
A non-invasive blood glucose measurement method using a magneto-resonance absorption method. A constant magnetic field is applied using a pair of permanent magnets, the magnetic field having a uniform strength. A triangular waveform low frequency modulation magnetic field is applied using a low frequency generator and a pair of low frequency coils, the low frequency modulation magnetic field having a uniform strength. A weak acoustic wave modulation magnetic field is applied using an acoustic wave generator and a pair of acoustic wave coils. Electromagnetic waves are applied to a detector in which a finger is positioned to produce a nuclear magneto-resonance, the electromagnetic waves having a frequency varying in a specific frequency band step by step, the applying being done using a high frequency generator and a sensor coil. A magneto-resonance absorption signal produced by spin-lattice relaxation of protons in a tissue of the finger because of the nuclear magneto-resonance is detected. A magneto-resonance spin-lattice relaxation time of the finger from the magneto-resonance absorption signal is determined. A blood glucose concentration in a human body is determined from a correlation between a pre-determined blood glucose concentration in the human body and the determined magneto-resonance spin-lattice relaxation time.

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Japanese Patent Office Action issued Jun. 17, 2008 with certification statement.

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