Non-crystalline minoxidil composition, its production and applic

Details Non-crystalline minoxidil composition, its production and applic Non-crystalline minoxidil composition, its production and applic

1987-03-30

1989-05-09

Lovering, Richard D.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

264 41, 264 46, 424 11, 424 45, 424449, 4284022, 436829, 514 78, 514944, 514947, 514969, A61K 3722, A61K 966, B01J 1302

Patent

active

048288373

ABSTRACT:
An aqueous, noncrystalline minoxidil composition for topical use. The composition contains minoxidil complexed with an amphipathic compound having a pK less than about 5 and containing a single lipophilic chain moiety and a sulfate, sulfonate, phosphate and phosphonate polar moiety. The composition may be formulated in ointment form, in an aqueous vehicle, or dispersed in a fluorochlorocarbon solvent, for spray delivery from a self-propelled spray device.

REFERENCES:
patent: 4654354 (1987-03-01), Shroot et al.
patent: 4670185 (1987-06-01), Fujiwara et al.

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