Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2008-05-27
2008-05-27
Schultz, J. Douglas (Department: 1635)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
Reexamination Certificate
active
07378509
ABSTRACT:
The present invention concerns double-stranded NF-κB decoy oligodeoxynucleotide (NF-κB dsODN) molecules that contain a core sequence capable of specific binding to an NF-κB transcription factor. In a particular aspect, the invention concerns NF-κB decoy molecules that preferentially bind p50/p65 and/or cRel/p50 heterodimers over p50/p50 homodimers. In another aspect, the invention concerns NF-κB decoy molecules with improved binding affinity to p65.
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Ehrhardt Rolf
McEvoy Leslie M.
Parham Christi
Zhang Jie
Anesiva, Inc.
De Vry Christopher
Dreger Ginger R.
Goodwin & Procter LLP
Schultz J. Douglas
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