Neisseria meningitidis antigens and compositions

Details Neisseria meningitidis antigens and compositions Neisseria meningitidis antigens and compositions

1999-04-30

2009-08-18

Devi, S. (Department: 1645)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C530S328000, C530S327000, C530S326000, C530S325000, C530S324000, C530S300000, C530S806000, C530S825000, C424S234100, C424S250100, C424S190100, C514S002600

Reexamination Certificate

active

07576176

ABSTRACT:
The invention provides proteins fromNeisseria meningitidis, including the amino acid sequences and the corresponding nucleotide sequences. The proteins are predicted to be useful antigens for vaccines and/or diagnostics.

REFERENCES:
patent: 5514581 (1996-05-01), Ferrari et al.
patent: 5550213 (1996-08-01), Anderson et al.
patent: 5554372 (1996-09-01), Hunter
patent: 5668004 (1997-09-01), O'Donnell
patent: 6060065 (2000-05-01), Barney et al.
patent: 6355253 (2002-03-01), Zlotnick
patent: 7018636 (2006-03-01), Bhattacharjee et al.
patent: 2004/0033234 (2004-02-01), Berinstein et al.
patent: 2007/0026021 (2007-02-01), Fraser et al.
patent: 0 818 465 (1998-01-01), None
patent: 01144977 (1989-06-01), None
patent: WO-92/13871 (1992-08-01), None
patent: WO-94/08013 (1994-04-01), None
patent: WO-96/01901 (1996-01-01), None
patent: WO-96/29412 (1996-09-01), None
patent: WO-96/33276 (1996-10-01), None
patent: WO-97/13860 (1997-04-01), None
patent: WO-97/37044 (1997-10-01), None
patent: WO-2006024954 (2006-03-01), None
Sambrook et al. Molecular Cloning, A Laboratory Manual, Second Edition, Cold Spring Harbor, pp. 17.1-17.44, 1989.
Campbell AM In: Monoclonal Antibody Technology. Elsevier Science Publishers, The Netherlands, Chapter 1, pp. 1-32, 1984.
The printed output from the NCBI open reading frame finder (12 pages provided as attachment).
Kohara Y. (Aug. 12, 1994). “Caenorhabditis elegans cDNA clone yk26f2: 5′ end, single read,” Database accession No. D35881. Database EMBL [Online] EBI.
Smith C.J. et al. (1995). “Nucleotide sequence determination and genetic analysis of the Bacteroides plasmid, pBI143,” Plasmid 34(3):211-222.
Dempsey J.A. et al. (Nov. 1995). “The physical map of the chromosome of a serogroup A strain ofNeisseria meningitidisshows complex rearrangement relative to the chromosomes of the two mapped strains of the closely related speciesN. gonorrhoeae,” Journal of Bacteriology 177(22):6390-6400.
Moxon, R.E. (Oct. 25, 1997). “Applications of molecular microbiology to vaccinology,” Lancet (North American Edition) 350(9086): 1240-1244.
Bernfield L. et al. (Sep. 2002). “Identification of a novel vaccine candidate for group BNeisseria meningitidis,” Thirteenth International PathogenicNeisseriaConference, Norwegian Institute of Public Health, Oslo, Norway, p. 116.
Farley J. et al. (Sep. 2002). “Characterization, cloning and expression of different subfamilies of the ORF 2086 gene fromNeisseria meningitidis,” Thirteenth International PathogenicNeisseriaConference, Norwegian Institute of Public Health, Oslo, Norway, p. 124.
Masignani V. (Mar. 17, 2003). “Vaccination againstNeisseria meningitidisusing three variants of the lipoprotein GNA1870,” J. Exp. Med. 197(6):789-799.
Fletcher L.D. et al. (Apr. 2004). “Vaccine potential of theNeisseria meningitidis2086 lipoprotein,” Infection and Immunity 72(4):2088-2100.
Baeumler, A. J. et al. (1993). “Hypothetical 29.6 kD Protein in PCP 5′ Region (ORF1),” Database Swissprot AC P31485.
Baumler, A. J. and K. Hantke (1992). “A Lipoprotein of Yersinia Enterocolitica Facilitates Ferrioxamine.Uptake inEscherichia coli,” Journal of Bacteriology 174(3): 1029-1035.
Blake, M. S. and L. M. Wetzler. (1995). “Vaccines for Gonorrhoea: Where are We on the Curve?” Trends in Microbiology 3(12): 469-474.
Burland, V. et al. (1994). “Escherichia coliK-12 Chromosomal Region From 92.8 to 00.1 Minutes,” Database Empro1 AC U14003.
Conlin, C. A. et al. (1992). “Escherichia coliprIC Encodes an Endopeptidase and is Homologous to theSalmonella typhimuriumopdA Gene,” Journal of Bacteriology 174(18): 5881-5997.
Dillard, J. P. et al. (1997) “A Peptidoglcan Hydrolase Similar to Bacteriophage Endolysins Acts as an Autolysin inNeisseria gonorrhoeae,” Molecular Microbiology 25(5): 893-907.
Fleischmann, R. D. et al. (1995). “Hypothetical Protein HI0753,” Database Swissprot AC P44861.
Fleischmann, R. D. et al. (1995). “Oligopeptidase A (EC 3.4.24.70),” Database Swissprot AC P44573.
Hacker, J. et al. (1993). “Immunophilins: structure-function relationship and possible role in microbial pathogenicity,” Molecular Microbiology 10(3): 445-456.
Huang, M. et al. (1995). “A Stomatin-Like Protein Necessary for Mechanosensation in C. Elegans,” Nature 378(6554); 292-295.
Kaneko, T. (1996). “Membrane-Bound Lytic Transglycosylase A MItA Synechocystis sp. Strain PCC 6803,” Database TrEMBLE AC Q55666.
Lommatzsch, J. et al. (1997). “Outer Membrane Localization of Murein Hydrolases: MItA, A Third Lipoprotein Lytic Transglycosynlase inEscherichia coli,” Journal of Bacteriology 179(17): 5465-5470.
Mcallister, C. F. and D. S. Stephens. (1993). “Analysis inNeisseria meningitidisand otherNeisseriaspecies of genes homologous to the FKBP Immunophilin family,” Molecular Microbiology 10(1): 13-23.
Mcallister, C. F. et al. (1993). “NeisseriaElongata NRL FKBP Immunophilin Homolog Gene,” Database Empro2 AC U001198.
Poolman, J. T. (1995). “Development of a Meningococcal Vaccine,” Infectious Agents and Disease 4(1): 13-28.
Quentin-Millet, M. J. et al. (1998) “N. MeningitidisHTR Tbp2 (de13777-385, de1407-465, de 1488-508),”Database GCQ—GenesEQAC W14640.
Rokbi et al. (1998). “Transferrin Binding Protein B, TbpB,Neisseria Meningitidis, ” Database TrEMBL AC 069750.
Rokbi, B. et al. (1997). “Evaluation of Recombinant Transferrin-Binding Protein B Variants fromNeisseria Meningitidisfor their Ability to Induce Cross-Reactive and Bactericidal Antibodies Against a Genetically Diverse Collection of Serogroup B Strains,” Infection and Immunity 65(1): 55-63.
Rokbi, B. et al. (1997). “Heterogenelty of tbpB, the transferrin-binding protein B gene, among serogroup BNeisseria meningitidisstrains of the ET-5 complex,” Clinical and Diagnostic Laboratory Immunology 4(5): 522-529.
Sampson, B. and E. C. Gotschlich. (1992). “Neisseria meningitidisencodes an FK506-inhibitable rotamase,” Proc. Natl. Acad, Sci. USA 89(4): 1164-1168.
Wong, C. Y. et al, (1997). “Cloning and characterization of two immunophilin-like genes, IIpA and fkpA, on a single 3.9-kilobase fragment of Aeromonas hydrophila genomic DNA,” Journal of Bacteriology 179(11): 3397-3403.
You, Z. et al. (1997). “Rhizobium EtliStomatin like Protein (slp) gene, complete cds.,” Database Empro1 AC AF034831.
You, Z. et al. (1998). “A Stomatin-Like Protein Encoded by the slp Gene ofRhizobium Etliis Required for Nodulation Competitiveness on the Common Bean,” Microbiology 144(9): 2619-2627.
1997-11-17-NM—shotgun.dbs (1928 pages) and 1997-12-15-NM.dbs (576 pages), located at <ftp://ftp.sanger.ac.uk/pub/pathogens
m/old data/>.
Declaration by Dr. Julian Parkhill dated Jun. 12, 2008. 2 pages.
Bernfield et al., and Farley et al. (Sep. 1-6, 2002).Thirteenth International Pathogenic Neisseria Conference, pp. 116 and 124.
Cantini et a l. (Mar. 2006). “Solution Structure of the Immunodominant Domain of Protective Antigen GNA 1870 ofNeisseria meningitidis,” Journal of Biological Chemistry281 (11): 7220-7227.
Fletcher et al. (2004). “Vaccine Potential of theNeisseria meningitidis2086 Lipoprotein,”Infection and Immunity72(4): 2088-2100.
Giuliani et al. (Feb. 2005). “The Region Comprising Amino Acids 100 to 255 ofNeisseria meningitidisLipoprotein GNA 1870 Elicits Bactericidal Antibodies,” Infection and Immunity 73(2): 1151-1160.
Lawrence, E. (1997). Henderson's Dictionary of Biological Terms, Eleventh Edition (1997). Longman Ltd. Definition of “epitope,” Cover pages, Table of Contents, and pp. 37 and 184.
Tettelin et al. (Mar. 2000). “Complete Genome Sequence ofNeisseria meningitidisSerogroup B Strain MC58,” Science 287: 1809-1815.
Welsch et al. (2004). &#x

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