Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-10-14
1999-03-02
Spivack, Phyllis G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514 27, A61K 3135, A61K 3170
Patent
active
058772081
ABSTRACT:
A method for inhibiting the activity of 3-hydroxy-3-methylglutaryl CoA(HMG--CoA) reductase in mammals is disclosed comprising administering naringin or naringenin thereto.
REFERENCES:
Pharmacol. Ther. 67(3):433-447, 1995, "New Targets For Lipid Lowering And Atherosclerosis Prevention", C.R. Sirtori.
"Molecular Biology Of The Cell", Third Edition, Garland Publishing, Inc. Bruce Alberts et al., p. 83 (1994).
"Principles of Biochemistry", 2nd Edition, Worth Publishers, AL Lehninger, 670-673 (1993).
McGilvery, R.W., Biochemistry, pub. W.B.Saunders, p. 593, 1970.
Choi, J. Nat. Products, 54(1), pp. 218-224, Jan., Feb. 1991.
Ahn Jung-Ah
Bae Ki-Hwan
Bok Song-Hae
Choi Doil
Choi Myung-Sook
Korea Institute of Science and Technology
Spivack Phyllis G.
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