N.sup.6 -[(2-Hydroxypropyl)aryl]adenosines

Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...

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536 26, 536 24, A61K 3170, C07H 1916

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active

043883087

ABSTRACT:
N.sup.6 -2-hydroxypropylaryl-substituted adenosines and adenines represented by the formula ##STR1## wherein R.sub.1 is selected from the group consisting of naphthyl, phenyl, substituted phenyl or biphenyl; and R.sub.2 is hydrogen or 1-.beta.-ribosyl; and the pharmaceutically acceptable salts thereof. The compounds are anti-hypertensive agents.

REFERENCES:
patent: 3929763 (1975-12-01), Fauland et al.
patent: 4138562 (1979-02-01), Vince
patent: 4221910 (1980-09-01), Sorolla
patent: 4309419 (1982-01-01), Wolberg et al.
patent: 4315000 (1982-02-01), Cook
patent: 4340730 (1982-07-01), Henderson et al.

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