N-phenyl-2-pyrimidine-amine derivatives

Details N-phenyl-2-pyrimidine-amine derivatives N-phenyl-2-pyrimidine-amine derivatives

2006-07-25

2006-07-25

Rao, Deepak (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C544S122000, C544S330000, C544S331000, C514S235800, C514S252180, C514S275000

Reexamination Certificate

active

07081532

ABSTRACT:
The invention relates to N-phenyl-2-pyrimidine-amine derivatives of formula (I)wherein the substituents are defined as in the description, to processes for the preparation thereof, to medicaments comprising those compounds, and the use thereof in the preparation of pharmaceutical compositions for the therapeutic treatment of warm-blooded animals, including humans.

REFERENCES:
patent: 5521184 (1996-05-01), Zimmermann
patent: 0 564 409 (1993-10-01), None
patent: WO 00/78731 (2000-12-01), None
Simone, Oncology: Introduction, Cecil Textbook of Medicine, 20thEdition, vol. 1, pp. 1004-1010, 1996.
Traxler, Protein tyrosine kinase inhibitors in cancer treatment, Exp. Opin. Ther. Patents, 7(6):571-588, 1997.
Tucker et al., Optimizing drug development: Strategies to assess drug metabolism/transporter interaction potential—toward a consensus, Clinical Pharamacology Therapeutics, vol. 70, No. 3, pp. 103-114, Aug. 2001.
Zimmerman et al., “Phenylamino-Pyrimidine (PAP)—Derivatives: A New Class of Potent and Highly Selective PDGF-Receptor Autophosphorylation Inhibitors”,Bioorg. Med. Chem. Lett., vol. 6, No. 11, pp. 1221-1226 (1996).

Affiliated with

Also associated with

Rating

N-phenyl-2-pyrimidine-amine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with N-phenyl-2-pyrimidine-amine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and N-phenyl-2-pyrimidine-amine derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3604705