N-(.omega.,(.omega.-1)-dialkyloxy)- and N-(.omega.,(.omega.-1)-d

Details N-(.omega.,(.omega.-1)-dialkyloxy)- and N-(.omega.,(.omega.-1)-d N-(.omega.,(.omega.-1)-dialkyloxy)- and N-(.omega.,(.omega.-1)-d

1989-10-27

1990-08-07

Killos, Paul J.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

A61K 950, A61K 4502

Patent

active

049467875

ABSTRACT:
This invention relates to compounds of the formula ##STR1## or an optical isomer thereof wherein R.sup.1 and R.sup.2 are the same or different and are an alkyl or alkenyl group of 6 to 24 carbon atoms; R.sup.3, R.sup.4 and R.sup.5 are the same or different and are alkyl of 1 to 8 carbon atoms, aryl, aralkyl of 7 to 11 carbon atoms, or when two or three of R.sup.3, R.sup.4, and R.sup.5 are taken together to form quinuclidino, piperidino, pyrrolidino, or morpholino; n is 1 to 8; and X is a pharmaceutically acceptable anion.

REFERENCES:
Malone, R. W. et al. Proc. Natl. Acad. Sci U.S.A., 86(16) 6077-6081 1989.
Felgner, P. L. et al, Proc. West. Pharmacol. Soc. 32 115-121 1989.
Tan et al. Biochem. Soc. Trans. 17(4) 690-691 1989.
Felger, P. et al Proc. Natl. Acad. Sci U.S.A., 84(21 7413-7417.

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