N-(4-(3-aminopropyl)aminobutyl)-2-(.omega.-gua nidino-fatty-acid

Details N-(4-(3-aminopropyl)aminobutyl)-2-(.omega.-gua nidino-fatty-acid N-(4-(3-aminopropyl)aminobutyl)-2-(.omega.-gua nidino-fatty-acid

1988-03-15

1991-01-08

Lone, Werren B.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260404, 564152, 564159, C09F 500, C09F 506

Patent

active

049833286

ABSTRACT:
N-[4-(3-Aminopropyl)aminobutyl]-2-(.omega.-guanidino-fatty acid-amido)-2-substituted-ethanamides represented by the general formula ##STR1## wherein Y represents --CH.sub.2 --CH.sub.2 --, --CH.dbd.CH or ##STR2## R represents a hydrogen atom, an alkyl group of 1 to 4 carbon atoms which may have a hydroxyl group as substituent, or a benzyl group, and n is an integer of from 1 to 8, provided that when Y is ##STR3## and n is 4, R represents the groups other than the hydrogen atom; salt thereof having antitumor activity in experimental animal tumors and a process for the preparation thereof is provided.

REFERENCES:
Morrison et al., Organic Chemistry, 3rd Edition, (1973), pp. 553-554.

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