N-(3-pyridylalkyl)sulfonamide compounds which have useful pharma

Details N-(3-pyridylalkyl)sulfonamide compounds which have useful pharma N-(3-pyridylalkyl)sulfonamide compounds which have useful pharma

1992-02-24

1994-12-20

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546338, 546333, C07D21342, H61K 3144

Patent

active

053746414

ABSTRACT:
Illustrative examples of the N-(3-pyridylalkyl)sulfonamide derivative are represented by the following formulae [II] and [III]: ##STR1## The derivatives are available for a thromboxane A.sub.2 production inhibitor, a thromboxane A.sub.2 antagonist, a prostaglandin H.sub.2 antagonist, an anti-thrombus agent, a thrombus-preventing agent and an anti-allergy agent.

REFERENCES:
patent: 4610981 (1986-09-01), Marsico, Jr. et al.
patent: 4874775 (1989-10-01), Krumkalns et al.
Susan Budavari et al., "The Merck Index", 1989, Merch & Co., Inc., Rahway, N.J. 11th Ed.; Abstract 2807: Daltroban, p. 2807.
H. Onishi et al. "Pharmaceuticals Containing N-picolylsulfonamide derivatives for Prevention of Thrombosis"; Chemical Abstracts, vol. 116, No. 11, (1992), Abstract No. 99325H.

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