N-(2-aryl-propionyl)-sulfonamides and pharmaceutical...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

Reexamination Certificate

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C564S182000

Reexamination Certificate

active

06881755

ABSTRACT:
The compounds of formula 1,wherein R and R2are as defined in the disclosure, are useful in the prevention and treatment of tissue damage due to exacerbated recruitment of polymorphonuclear neutrophils (PMN leukocytes) at the inflammatory sites.

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Kakeya et al., Tetrahedron Letters, vol. 32, No. 10, pp. 1343-1346 (1991).
Regit, Chemische Berichte, vol. 98, No. 4, pp. 1210-1024 (1965).
Belletire et al., Tetrahedron Letters, vol. 27, No. 2, pp. 131-134 (1986).

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