Mycarosyl macrolide antibiotics

Details Mycarosyl macrolide antibiotics Mycarosyl macrolide antibiotics

1973-09-06

1976-04-06

Brown, Johnnie R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424180, C07H 1700

Patent

active

039488845

ABSTRACT:
Covers the desisovaleryl derivative of niddamycin. Also covers a method of performing the microbial conversion of niddamycin, magnamycin A, magnamycin B, leucomycin A.sub.1 and leucomycin A.sub.3 to the corresponding desisovaleryl derivatives. These desisovaleryl derivatives are useful as antibiotics.

REFERENCES:
Macrolide Antibiotics, Encylopedia of Chem. Technology, Vol. 12, 1967, Wiley and Sons, pp. 632-661.
Omura et al., Studies on Chem. Structure . . . Their Related Macrolide Antibiotics, Progress in Antimicrobial and Anticancer Chemotherapy, Vol. 12, 1970, pp. 1043-1049.
Huber et al., Arzneimittel Forschung, Vol. 12, pp. 1191-1195, 1962.
Omura et al., "Among Leucomycins . . . Derivatives" J. of Antibiotics, Vol. 21, 1968, pp. 532-538.

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