Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Transferase other than ribonuclease
Patent
1995-09-28
1998-06-16
Wax, Robert A.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Transferase other than ribonuclease
435 75, 435 691, 4351723, 4352523, 43525233, 4353201, 536 232, C12N 910, C12N 1554, C12N 1570, C12P 1944
Patent
active
057669112
ABSTRACT:
A mutated farnesyldiphosphate synthase capable of synthesizing geranylgeranyldiphosphate and gene coding for said mutated enzyme, wherein the mutated enzyme is modified from a native farnesyldiphosphate synthase by mutation of a gene coding for a native farnesyldiphosphate synthase.
REFERENCES:
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Molecular and Cellular Biology, vol. 7, No. 9, (1987), pp. 3138-3146, Catherine F. Clarke et al.: Molecular Cloning and Sequence of a Cholesterol-Repressible Enzyme Related to Prenyltransferase in the Isoprene Biosynthetic Pathway.
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J. Biological Chemistry, vol. 264, (1989), pp. 19176-19184, Matt S. Anderson et al.: Farnesyl Diphosphate Synthetase --Molecular Cloning, Sequence, and Expression of an Essential Gene FromSaccharomyces Cerevisiae.
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J. Bacteriology, vol. 172, No. 12, (1990), pp. 6704-6712, Norihiko Misawa et al.: Elucidation of theErwinia uredovoraCarotenoid Biosynthetic Pathway by Functional Analysis of Gene Products LExpressed inEscherichia coli.
Tohoku Regional Meeting Of Allied Association Of Academic Associations in Chemical Field, 30 Sep. 1995, Shinichi Ohnuma et al.: Modification of Catalitic Function of Farnesyldi-phosphate Synthase by Random Mutagenesis.
Koike Ayumi
Koyama Tanetoshi
Nakazawa Takeshi
Nishino Tokuzo
Obata Shusei
Moore William W.
Toyota Jidosha & Kabushiki Kaisha
Wax Robert A.
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