Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1989-10-04
1993-06-15
Lee, Mary C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514452, 514466, 514471, 514603, 514616, 514620, A61K 3144, A61K 31335, A61K 3118, A61K 3116
Patent
active
052198715
ABSTRACT:
Compounds of the formula I ##STR1## wherein X, Y and v are as defined below, novel intermediates used in their synthesis, and the pharmaceutically acceptable salts of such compounds and intermediates. The compounds of formula I and the novel intermediates used in their synthesis are muscarinic receptor antagonists that are selected for smooth muscle muscarinic sites and are useful in the prevention and treatment of diseases associated with altered motility or tone of smooth muscle, such as irritable bowel syndrome, diverticular disease, urinary incontinence, aesophageal achalasia, and chronic obstructive airways disease.
REFERENCES:
patent: 4335122 (1982-06-01), McFadden et al.
Chemical Abstracts, 70(19), p. 293, Abstract No. 87390u (May 12, 1969).
Casy et al., J. Pharm. and Pharmacol., 19, 17-24 (1967).
Gualtieri et al., J. Med. Chem., 28, 1621-28 (1985).
Cross Peter E.
MacKenzie Alexander R.
DeBenedictis Karen
Ginsburg Paul H.
Lee Mary C.
McKane Joseph K.
Pfizer Inc.
LandOfFree
Muscarinic receptor antagonists does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Muscarinic receptor antagonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Muscarinic receptor antagonists will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1042967