Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals
Reexamination Certificate
2005-09-06
2005-09-06
Chin, Christopher L. (Department: 1641)
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
C436S536000, C436S063000, C436S523000, C435S006120, C435S007100, C435S007700, C435S007720, C435S007200, C435S007710, C435S007910, C435S007920, C435S007930, C435S973000
Reexamination Certificate
active
06939720
ABSTRACT:
A method for the multiplexed diagnostic and genetic analysis of enzymes, DNA fragments, antibodies, and other biomolecules comprises the steps of constructing an appropriately labeled beadset, exposing the beadset to a clinical sample, and analyzing the combined sample/beadset by flow cytometry. Flow cytometric measurements are used to classify, in real-time, beads within an exposed beadset and textual explanations, based on the accumulated data obtained during real-time analysis, are generated for the user. The inventive technology enables the simultaneous, and automated, detection and interpretation of multiple biomolecules or DNA sequences in real-time while also reducing the cost of performing diagnostic and genetic assays.
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Mack J. Fulwyler and Thomas M. McHugh, “Flow Microsphere Immunoassay for the Quantitative and Simultaneous Detection of Multiple Soluble Analytes”,Methods in Cell Biology, vol. 33, pp. 613-619.
Chandler Mark B.
Chandler Van S.
Fulton R. Jerrold
Chin Christopher L.
Daffer McDaniel LLP
Do Pensee T.
Huston Charles D.
Luminex Corporation
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