Monocyte chemoattractant protein-1 inhibitor compounds

Details Monocyte chemoattractant protein-1 inhibitor compounds Monocyte chemoattractant protein-1 inhibitor compounds

2005-10-11

2005-10-11

Powers, Fiona T. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S419000, C546S277400, C548S490000, C548S491000

Reexamination Certificate

active

06953809

ABSTRACT:
The invention concerns the use of a compound of formula (I), in which Z, X, T, A, R1, R2, p and q have any of the meanings defined herein, and their pharmaceutically acceptable salts or in vivo hydrolysable esters, in the treatment of a disease or condition mediated by monocyte chemoattractant protein-1 (MCP-1). Certain of the components of formula (I) are novel and are provided, together with pharmaceutical compositions thereof, as further features of the invention.

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