Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2006-06-27
2006-06-27
Guzo, David (Department: 1636)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C536S023100, C536S024500, C536S025200
Reexamination Certificate
active
07067497
ABSTRACT:
Modified oligonucleotides having a GGG motif sequence and a sufficient number of flanking nucleotides to modulate the telomere length of a chromosome are provided. Methods of modulating telomere length of a mammalian chromosome in vitro and in vivo are also provided, as are methods for inhibiting the division of a malignant mammalian cell and for modulating the effects of cellular aging.
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Anderson Kevin P.
Bennett C. Frank
Brown-Driver Vickie L.
Chiang Ming-Yi
Ecker David J.
Cozen O'Connor P.C.
Guzo David
ISIS Patent Department
ISIS Pharmaceuticals Inc.
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