Modified subtilisins and detergent compositions containing same

Details Modified subtilisins and detergent compositions containing same Modified subtilisins and detergent compositions containing same

1995-06-07

1997-09-09

Patterson, Jr., Charles L.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

435222, 4352523, 4353201, 510108, 510306, 536 232, C12N 952, C12N 954, C12N 956, C11D 3386

Patent

active

056655878

ABSTRACT:
The present invention relates to modified subtilisins comprising a mutation in an amino acid sequence of a subtilisin at a position selected from the group consisting of 1, 2, 3, 4, 6, 9, 10, 12, 14, 15, 17, 18, 19, 20, 21, 22, 24, 25, 27, 36, 37, 38, 40, 41, 43, 44, 45, 46, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 75, 76, 77, 78, 79, 87, 89, 91, 94, 97, 98, 99, 100, 101, 103, 104, 105, 106, 107, 108, 109, 112, 113, 115, 116, 117, 118, 120, 126, 128, 129, 130, 131, 133, 134, 136, 137, 140, 141, 143, 144, 145, 146, 155, 156, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 170, 171, 172, 173, 181, 182, 183, 184, 185, 186, 188, 189, 191, 192, 194, 195, 197, 204, 206, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 247, 248, 249, 251, 252, 253, 254, 255, 256, 257, 259, 260, 261, 262, 263, 265, 269, 271, 272 and 275. The present invention also relates to detergent compositions comprising a modified subtilisin of the present invention.

REFERENCES:
patent: 4760025 (1988-07-01), Estell et al.
patent: 4990452 (1991-02-01), Bryan et al.
patent: 4997763 (1991-03-01), Hughes et al.
patent: 5397705 (1995-03-01), Zukowski et al.
Siezen, R. J., et al., Protein Engineering, vol. 4, "Homology modelling and protein engineering strategy of subtilases, the family of subtilisin-like serine proteases", pp. 719-737 1991.
Wells et al., TIBS 13, Aug. 1988, pp. 291-297.
Russell et al., J. Mol. Biol., vol. 193, pp. 803-813 (1987).
Thomas et al., Nature, vol. 318, No. 28, pp. 375-376 (1985).
Wells et al., Phil. Trans. R. Soc. Lond., Chem. Abs., vol. 317(15) pp. 415-423 (1986).
Sternberg et al., Nature, vol. 330, pp. 86-88 (1987).
Russell et al., Nature, vol. 328, pp. 496-500 (1987).
Kurihara et al., J. Biol. Chem., vol. 247, No. 17, pp. 5619-5631 (1972).
Wells et al., Nucleic Acids Res., vol. 11, No. 22, pp. 7911-7925 (1983).
Stahl et al., J. Bacteriol, vol. 158, No. 2, pp. 411-418 (1984).
Vasantha et al., J. Bacteriology, vol. 159, No. 3, pp. 811-819 (1984).
Jacobs et al., Nucl. Acids. Res., vol. 13, No. 24, pp. 8913-8926 (1985).
Nedkov et al., Biol. Chem. Hoppe-Seyler, vol. 366, pp. 421-430 (1985).
Meloun et al., FEBS Lett., vol. 183, No. 2, pp. 195-200 (1985).
Jany and Mayer, Biol. Chem. Hoppe-Seyler, vol. 366, pp. 485-492 (1985).
Joseph Kraut, Ann. Rev. Biochem., vol. 46, pp. 331-358 (1977).
Wells et al., Proc. Natl. Acad. Sci. U.S.A., vol. 84, pp. 1219-1223 (1987).
Hwang and Warshel, Biochem., No. 26, pp. 2669-2673 (1987).
Rao et al., Nature, vol. 328, pp. 551-553 (1987).
Sorge et al., Abstract, J. Cell Biochem., suppl. 6, p. 343 (1982).
Naeve et al., Virology, vol. 129, pp. 298-308 (1983).
Svendsen et al., FEBS Lett 3361, vol. 196, No. 2, pp. 228-232 (1986).

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