Image analysis – Applications – Biomedical applications
Reexamination Certificate
2003-10-14
2009-10-20
Le, Brian Q (Department: 2624)
Image analysis
Applications
Biomedical applications
C382S129000, C382S130000, C382S131000, C382S132000, C382S133000, C382S134000
Reexamination Certificate
active
07606403
ABSTRACT:
In certain embodiments of the invention, a plurality of images of one or more subjects may be captured using different imaging techniques, such as different modalities of scanning probe microscopy. Parameters may be estimated from the plurality of images, using one or more models of known molecular structures to provide a model-based analysis. The estimated parameters may be fused, with further input from physical models of known molecular structures. The fused parameters may be used to characterize the subjects. Such characterization may include the detection and/or identification of specific molecular structures, such as proteins, peptides and/or nucleic acids of known sequence and/or structure. In some embodiments of the invention the structural characterizations may be used to identify previously unknown properties of a subject molecule.
REFERENCES:
patent: 4683195 (1987-07-01), Mullis
patent: 4683202 (1987-07-01), Mullis
patent: 4800159 (1989-01-01), Mullis
patent: 5405766 (1995-04-01), Kallury
patent: 5472881 (1995-12-01), Beebe et al.
patent: 5497656 (1996-03-01), Kado et al.
patent: 5603872 (1997-02-01), Margalit
patent: 5610287 (1997-03-01), Nikiforov
patent: 5612181 (1997-03-01), Fourmentin-Guilbert et al.
patent: 5621210 (1997-04-01), Lindsay
patent: 5624845 (1997-04-01), Wickramasinghe et al.
patent: 5776674 (1998-07-01), Ulmer
patent: 5840862 (1998-11-01), Bensimon et al.
patent: 5949070 (1999-09-01), Gamble
patent: 5986076 (1999-11-01), Rothschild
patent: 6013456 (2000-01-01), Khavan-Tafti
patent: 6044221 (2000-03-01), Gupta et al.
patent: 6054327 (2000-04-01), Bensimon et al.
patent: 6054495 (2000-04-01), Markowitz
patent: 6078681 (2000-06-01), Silver
patent: 6127120 (2000-10-01), Graham et al.
patent: 6139831 (2000-10-01), Shivashankar et al.
patent: 6149868 (2000-11-01), Natan et al.
patent: 6157921 (2000-12-01), Barnhill
patent: 6187823 (2001-02-01), Haddon
patent: 6195445 (2001-02-01), Dubuisson-Jolly et al.
patent: 6225055 (2001-05-01), Bensimon et al.
patent: 6225068 (2001-05-01), Wolfrum
patent: 6243106 (2001-06-01), Rehg et al.
patent: 6248537 (2001-06-01), Bensimon
patent: 6258401 (2001-07-01), Crowley
patent: 6259802 (2001-07-01), Jolly et al.
patent: 6265153 (2001-07-01), Bensimon et al.
patent: 6269172 (2001-07-01), Rehg et al.
patent: 6280939 (2001-08-01), Allen
patent: 6283812 (2001-09-01), Jin
patent: 6303296 (2001-10-01), Bensimon et al.
patent: 6327581 (2001-12-01), Platt
patent: 6344319 (2002-02-01), Bensimon et al.
patent: 6345235 (2002-02-01), Edgecombe et al.
patent: 6357285 (2002-03-01), Allen
patent: 6358375 (2002-03-01), Schwob
patent: 6360020 (2002-03-01), Panis
patent: 6396054 (2002-05-01), Kley
patent: 6545276 (2003-04-01), Sasaki
patent: 6547940 (2003-04-01), Aksay et al.
patent: 6689323 (2004-02-01), Fisher et al.
patent: 6905822 (2005-06-01), Barry et al.
patent: 2001/0052257 (2001-12-01), Magerle
patent: 2002/0013457 (2002-01-01), Suyama
patent: 2003/0087280 (2003-05-01), Schwartz et al.
patent: 2003/0138968 (2003-07-01), Fisher et al.
patent: 2004/0076996 (2004-04-01), Kondo et al.
patent: 0-404-682 (1990-12-01), None
patent: 0404682 (1990-12-01), None
patent: 0732-584 (1996-09-01), None
patent: 0732584 (1996-09-01), None
patent: 8256755 (1996-10-01), None
patent: 0161330 (2001-08-01), None
patent: WO 01/61330 (2001-08-01), None
Ando, et al., “ A High-Speed Atomic Force Microscope for Studying Biological Macromolecules,”PNAS, vol. 98, No. 22, pp. 12468-12472, Oct. 2001.
Clauss, et al., “Atomic Resolution STM Imaging of a Twisted Single-Wall Carbon Nanotube,”Physical Review B, vol. 58, No. 8, pp. 4266-4269, Aug. 1998.
Clauss, et al., “Electron Backscattering on Single-Wall Carbon Nanotubes Observed by Scanning Tunneling Microscopy,”Europhys. Lett.., 47(5), pp. 601-607, 1999.
Freitag, et al., “Local Electronic Properties of Single-Wall Nanotube Circuits Measured by Conducting-Tip AFM,”Physical Review B, vol. 62, No. 4, pp. 2307-2310, Jul. 2000.
Frisbie, et al, “Functional Group Imaging by Chemical Force Microscopy,”Science, vol. 265, pp. 2071-2074, Sep. 1994.
Hansma, et al., Atomic Force Microscopy of DNA in Aqueous Solutions,Nucleic Acids Res., 21:505-512, 1993.
Hirahara, et al., “One-Dimensional Metallofullerene Crystal Generated Inside Single-Walled Carbon Nanotubes,”Physical Review Letters, vol. 85, No. 25, pp. 5384-5387, Dec. 2000.
Huang, et al., “Directed Assembly of One-Dimensional Nanostructures into Functional Networks,”Science, vol. 291, pp. 630-633, Jan. 2001.
Kim, et al., “AFM Study of Surface Phenomena Based on C60Film Growth,”Applied Surface Science, 130-132, pp. 602-609, 1998.
Klein, et al., “Ordered Stretching of Single Molecules of Deoxyribose Nucleic Acid Between Microfabricated Polystyrene Lines,”Applied Physics Letters, vol. 78, No. 16, pp. 2396-2398, Apr. 2001.
Kobayashi, et al., “Imaging of Fullerene Molecules on Si(111)-7 7 Surface with NC-AFM,”Applied Surface Science, 157, pp. 228-232, 2000.
Möller, et al, “Tapping-Mode Atomic Force Microscopy Produces Faithful High-Resolution Images of Protein Surfaces,”Biophys. J., 77:1150-8, 1999.
Murray, et al., “Atomic Force Microscopy of Biochemically Tagged DNA,”Proc. Natl. Acad. Sci. USA, 90:3811-4, 1993.
Nicewarmer-Peña, “Submicrometer Metallic Barcodes,”Science, vol. 294, pp. 137-141, Oct. 2001.
Odom, et al., “Single-Walled Carbon Nanotubes,”Ann. N.Y. Acad. Sci., 960:203-215, (2002). Retrieved from the Internet on Jul. 2, 2002, URL://<http://annalsyas.org/cgi/content/full/960/1/203> 10 pages.
Thundat, et al., “Atomic Force Microscopy of DNA on Mice and Chemically Modified Mica,”Scanning Microsc. 6:911-8, 1992.
Uchihashi, et al, “Application of Noncontact-Mode Atomic Force Microscopy to Molecular Imaging,” Retrieved from the Internet on Jul. 3, 2002, URL://<http://www.foresight.org/Conferences/MNT7/Abstracts/Uchihashi/> 2 pages.
Epitaxial growth of copper phthalocyanine monolayers on Ag(111). J.Y. Grand et al. Surface Science. vol. 366. p. 403-414. 1996.
European Office Action dated Nov. 21, 2006, issued in connection to corresponding European Application No. 03809156.7.
Grand et al. (1996). “Expitaxial Growth of Copper Phtalocyanin Monolayers on Ag(111),”Surface Science366(3):403-414.
Berger & Kimmel,Guide to Molecular Cloning TechniquesAcademic Press, New York, NY. 1987.
Sambrook, et al,Molecular Cloning: A Laboratory Manual2ndEd. Cold Spring Harbor Press, Cold Spring Harbor, NY. 1989.
Protein Purification(1987). Scopes ed.; Springer-Verlag, New York, NY.
Methods in Molecular Biology: Protein Purification Protocolsvol. 59 (1996). Doonan ed.; Humana Press, Totowa, NJ.
Creighton (1984).Proteins: Structures and Molecular PropertiesCh. 5.; W.H. Freeman ed.; New York, NY.
Ramachandran et al. (1968).Adv. Protein Chem. 23:283-437.
Lee and Meisel, (1982): “Adsorption and Surface-Enhanced raman of Dyes on Silver and Gold Coils,”J. Phys. Chem. 86:3391-3395.
Feldheim, “Assembly of metal nanoparticle arrays using molecular bridges,” The Electrochemical Society Interface, Fall, 2001, pp. 22-25.
Parker et al. (1991). “High Yield Synthesis, Separation, and Mass-Spectrometric Characterization of Fullerenes C60to C266,”J.A. Chem. Soc. 113:7499-7503.
Schoenfeld et al. (1995). Proc. 7th1stint. Conf. on Modulated Semiconductor Structures, Madrid, 605-608.
Maivald et al. (1991). “Using Force Modulation to Image Surface Elasticities with the Atomic Force Microscope,”Nanotechnology2:103.
Chou & Fasman (1978).Adv. Enzymol. 47:45-148.
Bensimon, et al. (1995). “Stretching DNA with a Receding Meniscus: Experiments and Models,”Physical Review Letters74(23):4754-4757.
Michalet et al. (1997). “Dynamic Molecular Combing: Stretching the Whole Human Genome for High-Resolution Studies,”Science277:1518-1523.
Herrick et al. (2000). “Ouan
Berlin Andrew A.
Chan Selena
Hannah Eric
Haussecker Horst
Sundararajan Narayanan
Intel Corporation
Le Brian Q
Pillsbury Winthrop Shaw & Pittman LLP
LandOfFree
Model-based fusion of scanning probe microscopic images for... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Model-based fusion of scanning probe microscopic images for..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Model-based fusion of scanning probe microscopic images for... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4063114