Mobile phase dilution scheme for enhanced chromatography

Liquid purification or separation – With means to add treating material – Chromatography

Reexamination Certificate

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Details

Other Related Categories

C210S656000, C210S659000, C210S143000

Type

Reexamination Certificate

Status

active

Patent number

07875175

Description

ABSTRACT:
A method and device for increasing the loading capacity of a chromatography column through dilution of a mobile phase at the head of the column. A strong mobile phase is provided for dissolving a sample. A sample is injected into the strong mobile phase, and subsequently diluted with a weak mobile phase. The resulting sample-containing weak mobile phase is passed through a chromatography column for retention and separation of the components of the sample.

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