Microorganism for breaking down moenomycins, a process for the b

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

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435146, 435196, 4352525, 560186, C07C 5901, C07C 59125

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active

053150384

ABSTRACT:
A new microorganism for breaking down moenomycins, a process for the breakdown, and the use of the breakdown products are disclosed. A new Bacillus species and the appropriate enzymes obtained therefrom can be used to break down phosphoglycolipid antibiotics. The breakdown products of moenomycins display antibiotic activity or can be used as building blocks for the synthetic preparation of transglycosylase inhibitors.

REFERENCES:
Metten et al., Tetrahedron, 48 (39), pp. 8401-8418 (1992).
Hohgardt et al., Tetrahedron, 44 (18), pp. 5771, 5775 (1988).

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