Micellar nanoparticles

Details Micellar nanoparticles Micellar nanoparticles

1995-01-31

1997-05-13

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424470, A61K 914

Patent

active

056290217

ABSTRACT:
The present invention relates to micellar nanoparticles and methods of their production. Micellar nanoparticles are made by hydrating a mixture of an oil, a stabilizer/surfactant, and an alcoholic initiator with an aqueous solution. These micellar nanoparticles are normally less than 100 nanometers in diameter. The micellar nanoparticles are particularly advantageous in delivering materials such as estradiol topically through the skin because their small size allows easy penetration.

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Rolland, A. et al. (1992) "New Macromolecular Carriers for Drugs. I. Preparation and Characterization of Poly (oxyethylene-b-isoprene-b-oxyethylene) Block Copolymer Aggregates" Journal of Applied Polymer Science, 44: 1195-1203.

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