Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...
Reexamination Certificate
2008-07-22
2008-07-22
Saunders, David A. (Department: 1644)
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
C435S007100, C435S348000, C435S373000, C435S377000, C424S093700, C424S093710, C424S810000
Reexamination Certificate
active
07402430
ABSTRACT:
The present invention relates to synthetic antigen-presenting matrices, their methods of making and their methods of use. One such matrix is cells that have been transfected to produce MHC antigen-presenting molecules with one or more accessory molecules. The matrices are used to activate naive CD4+T cells as well as shift the ongoing activation state into a preferred differentiated population of either Th1 or Th2 cells.
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Jackson Michael R.
Karlsson Lars
Peterson Per A.
Webb Susan R.
Winqvist Ola
Fitting Thomas
McCarthy Michael J.
Saunders David A.
The Scripps Research Institute
VanderVegt F. Pierre
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