Methods of using lysophosphatidic acids for regulating skin wrin

Drug – bio-affecting and body treating compositions – Designated organic nonactive ingredient containing other... – Carboxylic acid ester

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252106, 252107, 424DIG5, 424 47, 424 59, 424 60, 424 63, 424 64, 424450, 514725, 514784, 514836, 514847, 514873, 514938, 514944, 514946, 514947, 514969, 514120, 514110, 514844, A61K 742, A61K 748, A61K 910, C11D 348

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055212239

ABSTRACT:
The subject invention relates to methods for regulating wrinkles in mammalian skin comprising topical application of a lysophosphatidic acid compound having the structure: ##STR1## or a cyclic derivative thereof having the structure: ##STR2## or a pharmaceutically acceptable salt thereof, wherein --R is unsubstituted or substituted, saturated or unsaturated, straight or branched chain alkyl having from 12 to about 23 carbon atoms; each --X-- is independently --O-- or --S--; and --Y-- is --O-- or --CH.sub.2 --.

REFERENCES:
patent: 5238965 (1993-08-01), Piazza et al.

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