Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2011-03-29
2011-03-29
Marschel, Ardin (Department: 1614)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S210120, C514S252010, C514S385000, C514S579000
Reexamination Certificate
active
07915246
ABSTRACT:
The present invention provides a method of treating fibromyalgia syndrome (FMS), chronic fatigue syndrome (CFS), and pain in an animal subject. The method generally involves administering a therapeutically effective amount of a dual serotonin norepinephrine reuptake inhibitor compound or a pharmaceutically acceptable salt thereof, wherein said dual serotonin norepinephrine reuptake inhibitor compound is characterized by a non-tricyclic structure and an equal or greater inhibition of norepinephrine reuptake than serotonin reuptake. In particular, the use of milnacipran to treat FMS, CFS, and pain is disclosed.
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Shuto et al., Synthesis and Biological Activity of Conformationally Restricted Analogs of Milnacipran: (1s,2R)-1-P
Kranzler Jay D.
Rao Srinivas G.
Cypress Bioscience, Inc.
Finnegan Henderson Farabow Garrett & Dunner LLP
Hughes Alicia R
Marschel Ardin
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