Methods of treating cryptosporidium parvum

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514269, 544242, 544296, 544298, 544322, 544326, A61K 31505, C07D23926

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active

056229550

ABSTRACT:
The present invention provides methods for treating Cryptosporidium parvum in a subject in need of such treatment. The methods comprises administering to the subject a compound of Formula I: ##STR1##

REFERENCES:
patent: 5521189 (1996-05-01), Boykin et al.
B.P. Das et al; 1,4 Bis(4guanylphenylethyl)benzenes as Potential Antitrypanosomal Agents, Journal of Pharmaceutical Sciences 71: pp. 465-466 (1982).
B.P. Das et al; Synthesis and Antiprotozoal Activity of 2,5-Bis(4-guanylphenyl)furans, Journal of Medicinal Chemistry 20, pp. 531-536 (1977).
B.P. Das et al; Snythesis and Antiprotozoal Activity of 2,5-Bis(4-guanylphenyl)thiophenes and -pyrroles, Journal of Medicinal Chemistry 20, pp. 1219-1221 (1977).
B.P. Das et al; Synthesis and Antitrypanosomal Activity of Some Bis(4-guanylphenyl) Five-and Six-Membered Ring Heterocycles, J. Med. Chem. 23, pp. 578-581 (1980).
C. C. Dykstra et al; Synthesis and Characterization of a Novel Series of Aromatic Dicationic Furans With DNA-Specific Fluorescence Properties, pp. 1-7 (1994).
D.E. Rooney et al; Human Cytogenetics: A Practical Approach, ed. IRL Press, Oxford University Press, selected pages (1992).

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