Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving hydrolase
Reexamination Certificate
2007-04-24
2007-04-24
Gitomer, Ralph (Department: 1657)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving hydrolase
C435S024000, C435S375000, C530S300000
Reexamination Certificate
active
11027949
ABSTRACT:
The present provides compounds capable of modulating IL-4 receptor-mediated IgE production, as well as IL-4 induced processes associated therewith, methods and kits for identifying such compounds that utilize a CLLD8 protein as a surrogate analyte and methods of using the compounds in a variety of in vitro, in vitro and ex vivo contexts.
REFERENCES:
patent: 6979549 (2005-12-01), Masuda et al.
patent: 2004/0014638 (2004-01-01), Masuda et al.
Mabuchi et al., “Cloning and Characterization of CLLD6, CLLD7, and CLLD8, Novel Candidate Genes for Leukemogenesis at Chromosome 13q14, a Region Commonly Deleted in B-Cell Chronic Lymphocytic Leukemia,” Cancer Res. 61:2870-2877 (2001).
Anderson David C.
Bennett Mark K.
Kinoshita Taisei
Kinsella Todd M.
Masuda Esteban
Diehl James J.
Francis Carol L.
Gitomer Ralph
Keddie James S.
Rigel Pharmaceuticals Inc.
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