Chemistry: electrical current producing apparatus – product – and – Fuel cell – subcombination thereof – or method of making or... – Process or means for producing – recycling – or treating...
Patent
1995-05-24
1999-02-16
Bawa, Raj
Chemistry: electrical current producing apparatus, product, and
Fuel cell, subcombination thereof, or method of making or...
Process or means for producing, recycling, or treating...
424423, 424424, 424426, 424427, 424430, 424434, 424437, 424489, 424490, A61K 950, A61K 914
Patent
active
058717676
ABSTRACT:
A method for treatment of a neurodegenerative condition in a patient comprising implanting in the patient at least one immunoisolatory vehicle comprising a corc comprising a volume of at least 1 .mu.l and at least 10.sup.4 living cells which secrete at least one biologically active product, said cells being dispersed in a biocompatible matrix comprising a hydrogel or extracellular matrix components, and an external jacket surrounding the core, the jacket comprising a biocompatible hydrogel or thermoplastic, the jacket being free of cells projecting externally thereof, said jacket having a molecular weight cutoff permitting the passage of the biologically active product from the core through the jacket.
REFERENCES:
patent: 3093831 (1963-06-01), Jordan
patent: 3615024 (1971-10-01), Michaels
patent: 4251387 (1981-02-01), Lim et al.
patent: 4298002 (1981-11-01), Ronel
patent: 4324683 (1982-04-01), Lim et al.
patent: 4352883 (1982-10-01), Lim
patent: 4353888 (1982-10-01), Sefton
patent: 4391909 (1983-07-01), Lim
patent: 4407957 (1983-10-01), Lim
patent: 4409331 (1983-10-01), Lim
patent: 4479796 (1984-10-01), Kallok
patent: 4663286 (1987-05-01), Tsang et al.
patent: 4670014 (1987-06-01), Huc
patent: 4686098 (1987-08-01), Kopchick
patent: 4689293 (1987-08-01), Goosen
patent: 4749620 (1988-06-01), Rha
patent: 4789550 (1988-12-01), Hommel
patent: 4806355 (1989-02-01), Goosen
patent: 4868121 (1989-09-01), Scharp
patent: 4883666 (1989-11-01), Sabel
patent: 4892538 (1990-01-01), Aebischer
patent: 4902295 (1990-02-01), Walthall
patent: 4942129 (1990-07-01), Goosen
patent: 4960415 (1990-10-01), Reinmuller
patent: 5002661 (1991-03-01), Chick
patent: 5026365 (1991-06-01), Rossini
patent: 5082670 (1992-01-01), Gage
patent: 5084350 (1992-01-01), Chang
patent: 5106627 (1992-04-01), Aebsicher
patent: 5156844 (1992-10-01), Aebischer
patent: 5158881 (1992-10-01), Aebischer et al.
patent: 5283187 (1994-02-01), Aebischer et al.
patent: 5284761 (1994-02-01), Aebischer et al.
patent: 5292515 (1994-03-01), Moro
patent: 5389535 (1995-02-01), Aebischer et al.
Aebischer et al., Trans. Am. Soc. Artif. Intern. Organs, vol. XXXII, pp. 134-137 (1986).
Aebischer et al., Biol. Abstr., 91, p. 762 (1991).
Aebischer et al., Biomaterials, 12 pp. 50-56 (1991).
Aebischer et al., Brain Research 560, pp. 43-49 (1991).
Aebischer et al., Exp. Neurol., 111, pp. 269-275 (1991).
Aebischer et al., J. Biomech. Eng., 113, pp. 178-183 (1991).
Aebischer and Goddard, Science, 252, p. 133 (1991).
Algire et al. J. National Cancer Institute, 15, pp. 493-507 (1954).
Altman et al., Trans. Am. Soc. Artif. Intern. Organs, vol. XXX, pp. 382-386 (1984).
Altman et al., Diabetes, 35, pp. 625-633 (1986).
Amicon Corp. Publication No. 442C, pp. 1-4.
Archer et al., J. Surgical Research, 28, pp. 77-85 (1980).
Bontempo et al., Blood, 69, pp. 1721-1724 (1987).
Brandrup et al., Polymer Handbook 3rd Ed., John Wiley & Sons, N.Y. (1989).
Britt et al., Diabetes, 30, pp. 580-583 (1981).
Cabasso, Encyclopedia of Chemical Technology, Kirk Othmer, ed., Wiley, NY, 12, pp. 492-517 (1980).
Cai et al., Artificial Organs, 12, pp. 388-393 (1988).
Cepko, Neuron, 1, pp. 345-353 (1988).
Christenson et al., J. Biomed. Mat. Res., 23, pp. 705-718 (1989).
Christenson, Ph.D. Thesis, Brown University (1990).
Cohen et al., J. Am. Chem. Soc., 112, pp. 7832-7833 (1990).
Cole et al., Diabetologia, 35, pp. 231-237 (1992).
Darquy et al., Diabetologia, 28, pp. 776-780 (1985).
Darquy et al., Trans. Am. Soc. Artif. Intern. Organs, vol. XXXIII, pp. 356-358 (1987).
Dionne, Thesis Ph.D., Massachusetts Institute of Technology, pp. 170-184 (1989).
Dupuy et al., J. Biomed. Mat. Res., 22, pp. 1061-1070 (1988).
Edmunds et al., Applied Biochemistry and Biotechnology, 20-21, pp. 603-619 (1989).
Faithfull, Anaesthesia, 42, pp. 234-242 (1987).
Fan et al., Diabetes 39, pp. 519-522 (1990).
Fu et al., Transplantation, 47, pp. 432-435 (1989).
Gordon et al., Nature, 326, pp. 403-405 (1987).
Hama et al., Pain, 52, pp. 223-231 (1993).
Hoffman et al., Exp. Neurol., 110, pp. 39-44 (1990).
Hong et al., Int. J. Radiation Oncology Biol. Phys. 16, pp. 1097-1099 (1989).
Iwata et al., Diabetes, 38, pp. 224-225 (1989).
Jaeger et al., Progress in Brain Research, 82, pp. 41-46, Elsevier Science Publishers B.V. (1990).
Jaeger et al., Brain Research, 551, pp. 163-170 (1991).
Jarret et al., The Lancet, 2, pp. 1009-1012 (1976).
Jolley et al., Transplantation Proceedings, IX, pp. 363-365 (1977).
Klomp et al., Journal of Biomedical Materials Research, 17, pp. 865-871 (1983).
Lacy et al., Science, 204, pp 312-313 (1979).
Lacy et al., Science, 254, pp. 1782-1784 (1991).
Land et al., Nature, 304, pp. 596-602 (1983).
Leung et al., Artificial Organs, 7, pp. 208-212 (1983).
Lim et al., Science, 210, pp. 908-910 (1980).
Livett, Physiology Reviews, 64, pp. 1103-1161 (1984).
Maniats et al., Can. J. Comp. Med., 42, pp. 428-437 (1978).
Matthews et al., Recent Advances in Germfree Research, Tokai University Press, pp. 61-64 (1981).
NASA Tech. Briefs MSC-21480, U.S. Gov't. Printing Office, Washington, D.C.
NASA Tech. Briefs NPO-17517, vol. 15 #page 54, U.S. Gov't. Printing Office, Washington, D.C.
O'Shea et al., Biochim. Biophys. Acta., 804, pp. 133-136 (1984).
O'Shea et al., Diabetes, 35, pp. 943-946 (1986).
Reach, Biomed. Biochim. Acta, 43, pp. 569-576 (1984).
Ricordi et al., Transplantation, 45, pp. 1148-1151 (1988).
Ronel et al., Journal of Biomedical Materials Research, 17, pp. 855-864 (1983).
Sagen et al., Proc. Natl. Acad. Sci. USA, 83, pp. 7522-7526 (1986).
Sagen et al., Pain, 42, pp. 69-79 (1990).
Sagen et al., J. Neuroscience, 13, pp. 2415-2423 (1993).
Sanberg et al., Exp. Neurol., 66, pp. 444-466 (1979).
Scharp et al., World J. Surg., 8, pp. 221-229 (1984).
Sefton et al., Biotech. and Bioeng., XXIX, pp. 1135-1143 (1987).
Short et al., Dev. Neurosci., 12, pp. 34-45 (1990).
Soeldner et al., Diabetes, 14, pp. 771-779 (1965).
Sugamori et al., Trans. Am. Soc. Artif. Intern. Organs, XXXV, pp. 791-799 (1989).
Sun et al., Diabetes, 26, pp. 1136-1139 (1977).
Sun et al., Applied Biochem. Biotechnol., 10, pp. 87-99 (1984).
Sun et al., Trans. Am. Soc. Artif. Intern. Organs, XXXII, pp. 39-41 (1986).
Sun et al., Biomat., Art. Cells, Art. Org., 15, pp. 483-496 (1987).
Sun et al., CRC Critical Reviews in Therapeutic Drug Carrier Systems, 4, pp. 1-12 (1987).
Sun, Trans. Am. Soc. Artif. Intern. Organs, XXXIII, pp. 787-790 (1987).
Sun, Methods in Enzymology, 137, pp. 575-580 (1988).
Tresco et al., ASAIO Journal, 38, pp. 17-23 (1992).
Tze et al., Nature, 264, pp. 466-467 (1976).
Tze et al., Diabetologia, pp. 247-252 (1979).
Tze et al., Transplantation, 33, pp. 563-564 (1982).
Weber et al., Transplantation, 49, pp. 396-404 (1990).
Will et al., Behav. Brain Res., 17, pp. 17-24 (1985).
Wilson et al., J. Biol. Chem., 263, pp. 2712-2718 (1988).
Winn et al., Exp. Neurol., 105, pp. 244-250 (1989).
Winn et al., J. Biomed. Materials Res., 23, pp. 31-44 (1989).
Winn et al., Exp. Neurol., 113, pp. 322-329 (1991).
Winnie et al., Anesthesiology, 79, pp. 644-653 (1993).
Wu et al., Int'l. Jour. Pancreatology, 3, pp. 91-100 (1988).
Wu et al., Trans. Am. Soc. Artif. Intern. Organs, XXXV, pp. 736-738 (1989).
Aebischer Patrick
Christenson Lisa
Dionne Keith E.
Emerich Dwaine F.
Gentile Frank T.
Bawa Raj
Brown University Research Foundation
Ekrufu Ivor R.
LandOfFree
Methods for treatment or prevention of neurodegenerative conditi does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods for treatment or prevention of neurodegenerative conditi, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for treatment or prevention of neurodegenerative conditi will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2059851