Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Using tissue cell culture to make a protein or polypeptide
Patent
1993-07-27
1995-02-14
Nucker, Christine M.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Using tissue cell culture to make a protein or polypeptide
435 702, 4351722, 43524023, 5303888, 53038885, 530809, 530867, C07K 1528, C12P 2108, C12N 1502
Patent
active
053895304
ABSTRACT:
The present invention relates to an improved method for the production of antibodies to tumor-associated gangliosides using ganglioside lactones. The resulting antibodies are useful in the detection and treatment of tumors containing gangliosides. The present invention also relates to methods of treatment of tumors by active immunization using ganglioside lactones.
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Proc. Natl. Acad. Sci., vol. 82, pp. 1242-1246, Feb. 1985, "Mouse monoclonal IgG3 antibody detecting G.sub.D3 ganglioside: A phase I trail . . . melanoma", Alan N. Houghton et al.
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Cunningham Thomas
Nucker Christine M.
The Biomembrane Institute
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