Methods for stimulating follicular growth

Details Methods for stimulating follicular growth Methods for stimulating follicular growth

1997-07-08

1998-05-26

Witz, Jean C.

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Hydrolases

424574, 514 2, 514 21, A61K 37547

Patent

active

057560943

ABSTRACT:
A method of modulating hair growth by contacting selected cells with a selected growth-modulating molecule is provided. A method for hair reconstitution or transplantation by expanding selected cells in vitro and combining them with other cells that regulate hair growth are also provided. Compositions containing a growth-modulating molecule which is synthesized by follicular cells and which undergoes hair-cycle-dependent concentration changes in hair follicles are also provided.

REFERENCES:
patent: 4596812 (1986-06-01), Chidsey, III et al.
patent: 5026691 (1991-06-01), Kligman
patent: 5053403 (1991-10-01), Orentreich et al.
patent: 5094857 (1992-03-01), Luderschmidt
patent: 5112608 (1992-05-01), Scott et al.
patent: 5134076 (1992-07-01), Cunningham et al.
patent: 5187089 (1993-02-01), Scott et al.
patent: 5196196 (1993-03-01), Scott et al.
patent: 5206017 (1993-04-01), Scott
patent: 5326562 (1994-07-01), Scott
patent: 5352442 (1994-10-01), Proctor
Chomcqynski and Sacchi, "Single-Step Method of RNA Isolation by Acid Guanidinium Thoicyanate Phenol-Chloroform Extraction" Anal. Biochem. 1987, 162: 156-159.
Cotsarelis et al., "Existence of Slow-Cycling Limbal Epithelial Basal Cells That Can Be Preferentially Stimulated to Proliferate: Implications on Epithelial Stem Cells", in Cell 1989, 57: 201-209.
Cotsarelis et al., "Label-Retaining Cells Reside in the Bulge Area of Pilosecbaceous Unit: Implications for Follicular Stem Cells, Hair Cycle and Skin Carcinogenesis", Cell 1990, 61: 1329-1337.
Jahoda and Oliver, "The growth of vibrissa dermal papilla cells in vitro", Br. J. Derm. 1981, 105: 623-627.
Johoda and Oliver, "Vibrissa dermal papilla cell aggregative behaviour", J. Embryol. exp. Morph. 1984, 79: 211-224.
Kobayashi et al., "Segregation of keratinocyte colony-forming cells in the bulge of the rat vibrissa," PNAS USA 1993 90: 7391-7395.
Liang and Pardee, "Differential Display of Eukaryotic Messenger RNA by Means of the Polymerase Chain Reaction", Science 1992, 257: 967-971.
Rochat et al., "Location of Stem Cells of Human Hair Follicles by Clonal Analysis", Cell 1994, 76: 1063-1073.
Warren et al., "Improved Method for the Isolation and Cultivation of Human Scalp Dermal Papilla Cells", J. Invest. Derm. 1992, 98: 693-699.
Yang et al. "Upper Human Hair Follicle Contains a Subpopulation of Keratinocytes with Superior In Vitro Proliferative Potential", J. Invest. Derm. 1993, 101: 652-659.

Affiliated with

Also associated with

Rating

Methods for stimulating follicular growth does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods for stimulating follicular growth, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for stimulating follicular growth will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1957276