Methods for making tetrahydroisoalpha and hexahydroisoalpha acid

Food or edible material: processes – compositions – and products – Products per se – or processes of preparing or treating... – Hop derived ingredient – including hopping of wort

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426422, 568377, C12C 300

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active

050135716

ABSTRACT:
A method of converting alpha acids to hop flavors by exposing the alpha acids to an environment capable of substantially simultaneously isomerizing and reducing the alpha acids to form either THIAA or HHIAA. Another aspect of this invention is directed to a method of reducing hop flavors by exposing an isoalpha acid, a dihydroisoalpha acid or a mixture thereof to conditions suitable to reduce said acids to produce THIAA, HHIAA or a mixture thereof at a pH of about 5 to about 12 in a reaction inert, protic solvent. Yet another aspect of this invention is directed to a method of reducing hop flavors comprising exposing an isoalpha acid, a dihydroisoalpha acid or a mixture thereof to conditions suitable to reduce said acids to produce THIAA, HHIAA or a mixture thereof in a reaction inert, aprotic solvent.

REFERENCES:
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patent: 4590296 (1986-05-01), Cowles
patent: 4644084 (1987-02-01), Cowles
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Carson, J. F., "The Alkaline Isomerization of Humulone", Isohop Hydrogenation In Exptl., 74: 4615-4620 (1952).
Byrne et al., "Reduction Products from cis-and trans-Isocohumulone", J. Chem. Soc. (C), pp. 2810-2813 (1971).
Brown et al., "Chemistry of Hop Constituents, Part XIII", The Hydrogenation of IsoHumulone, pp. 545-551, (1959).
Verzele et al., "On the Hydrogenation of Humulone, Part I", Bull. Soc. Chim. Belg. 68: 315-324, 6 fig., (1959).
Anteunis et al., "On the Hydrogenation of Humulone, Part II", Bull. Soc. Chim. Belg., 68: 476-583, 1 fig. (1959).
DeKeukeleire et al., "The Structure of the Absolute Configuration of (-)Humulone", Tetrahedron, 26: 385-393 (1970).
Verzele, M., "The Chemistry of Hops", Brewing Science, vol. 1, Chapter 4, pp. 279-323 (1979).
DeKeukeleire et al., "Regiospecific Singlet Oxygen Oxidation of (-)R-Tetrahydrohumulone and Hexahydrocolupulone", Bull. Soc. Chim. Belg. 85, No. 5: 293-304, (1976).
Meheus et al., "Humulinone", Bull. Soc. Chim. Belg. 73: 268-273, 3 fig. (1964).

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